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Krishna Mahadevan

Chemical Engineering and Biotechnology / University of Toronto /

Research Areas

Clean Energy
Artificial Intelligence


Krishna Mahadevan is a Professor in the Departments of Chemical Engineering & Applied Chemistry, and Institute of Biomaterials and Biomedical Engineering and a Canada Research Chair in Metabolic Systems Engineering at the University of Toronto. He obtained his B. Tech from Indian Institute of Technology, Madras in Chemical Engineering in 1997 and then obtained his Ph.D. degree from the University of Delaware in Chemical Engineering in 2002. He was a research scientist at Genomatica Inc., San Diego from 2002–06 and has also held appointments as a visiting scholar and a guest lecturer at the Department of Bioengineering in the University of California, San Diego, and in the Department of Microbiology, University of Massachusetts, Amherst. His research interests are in the area of modeling, analysis and optimization of metabolism for applications in bioremediation, biochemicals production and medicine and has published over 130 articles in these areas.  He has received AIChE’s David W. Smith Jr. Best Paper Award in 2006, the Jay Bailey Young Investigator Award in Metabolic Engineering in 2010, the Society of Industrial Microbiology and Biotechnology’s Young Investigator Award in 2012, the Syncrude Innovation Award in 2014, Biochemical Engineering Journal Young Investigator award in 2017 and the D. G. Fisher Award from CsChE in 2021.

Research Interests

Systems biology, synthetic biology, metabolic engineering, metabolic modeling and model-based design, bioprocess optimization & control, artificial intelligence, machine learning, dynamic control of metabolism, industrial biotechnology for biochemicals and biofuels, environmental biotechnology, Carbon fixation, biomedical systems, human metabolism, gut microbiome, pharmacokinetic and pharmacodynamic modeling, personalized nutrition and medicine.


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